Population scale HLA-typing and uses thereof
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United States of America Patent
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May 22, 2012
Grant Date -
Nov 4, 2010
app pub date -
Feb 18, 2010
filing date -
Feb 27, 2006
priority date (Note) -
Expired
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Abstract
The present invention provides a portable system for real-time population-scale HLA genotyping and/or allelotyping in a field environment and methods of such population-scale HLA genotyping. The individual components of the system are portable to and operable within a field environment thereby providing high throughput with real-time geno- or allelotyping. Also provided are HLA gene-specific primers and HLA allele-specific or single nucleotide polymorphism-specific hybridization probes. In addition the present invention provides a microarray comprising the hybridization probes. Further provided is a kit comprising the HLA gene-specific primers and the microarray.
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