Process for enantioselective synthesis of single enantiomers of thio-substituted arylmethanesulfinyl derivatives by asymmetric oxidation

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United States of America Patent

PATENT NO 8183294
APP PUB NO 20110098505A1
SERIAL NO

12984279

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention relates to a method for preparing a sulphoxide compound of formula (I) either as a single enantiomer or in an enantiomerically enriched form, comprising the steps of:

    a) contacting a pro-chiral sulphide of formula (II) with a metal chiral complex, a base and an oxidizing agent in an organic solvent; and optionallyb) isolating the obtained sulphoxide of formula (I).

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Patent Owner(s)

  • TEVA SANTE;CEPHELON FRANCE

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Louvet, Philippe Montgeron, FR 8 32
Schweizer, Dominique Paris, FR 4 10

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