Pyridone derivatives as p38α MAPK inhibitors

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United States of America Patent

PATENT NO 8173684
APP PUB NO 20100063098A1
SERIAL NO

12597926

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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A compound represented by the formula (I): wherein R1 is lower alkyl, cycloalkyl or aromatic hydrocarbon ring, each of which is optionally substituted with one or more substituents; R2 is hydrogen atom, halogen atom, lower alkyl, halo(lower)alkyl or lower alkoxy; and R3 is (1) a group represented by the formula: wherein R4 is lower alkyl, etc.; (2) a group represented by the formula: wherein R5 is lower alkyl, etc.; (3) a group represented by the formula: wherein R6 is lower alkyl, etc.; or (4) a group selected from halogen atom, carboxy, hydroxy and lower alkoxy, or a salt thereof.

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Patent Owner(s)

Patent OwnerAddress
ASTELLAS PHARMA INC5-1 NIHONBASHI-HONCHO 2-CHOME CHUO-KU TOKYO 103-8411 JAPAN
WAKUNAGA PHARMACEUTICAL CO LTD5-36 MIYAHARA 4-CHOME YODOGAWA-KU OSAKA-SHI OSAKA 532-0003

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kasahara, Chiyoshi Chuo-ku, JP 17 231
Yamazaki, Hitoshi Chuo-ku, JP 93 1222

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