Modulation of mesenchymal and metastatic cell growth
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United States of America Patent
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May 8, 2012
Grant Date -
Apr 26, 2007
app pub date -
Sep 22, 2006
filing date -
Sep 22, 2005
priority date (Note) -
Expired
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Abstract
The present invention relates to compositions and methods for the modulation of metastatic and mesenchymal cell growth and mobility via the regulation of the formation of Twist/Twist homodimers and Twist/E heterodimers. The present invention also relates to methods for screening agents and compound libraries for molecules that function to modulate the formation of Twist/Twist homodimers, Twist/E protein heterodimers or their upstream or downstream effector molecules.
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