Vinblastine derivatives, their preparation, use and pharmaceutical compositions comprising the said derivatives
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United States of America Patent
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May 1, 2012
Grant Date -
May 6, 2010
app pub date -
Dec 17, 2007
filing date -
Jan 29, 2007
priority date (Note) -
Expired
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Abstract
The invention provides vinblastine derivatives represented by the following formula 1 or their physiologically acceptable salts, their preparation, use and pharmaceutical compositions comprising the said derivatives. The said vinblastine derivatives show inhibiting activities against tumor cell lines and can be used as medicaments for treating malignant tumors.
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