Process for the preparation of Rho-kinase inhibitor compounds
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United States of America Patent
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Apr 17, 2012
Grant Date -
Jan 28, 2010
app pub date -
May 21, 2009
filing date -
Jun 18, 2008
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Expired
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Abstract
The present invention is directed to practical high-yielding synthetic processes to prepare compounds of general Formula III, IV, V, VII, VIII, IX, X, XII, XIV, and XV. Such compounds are useful as final products or can be used as intermediates and be further modified to prepare other desired products such as rho-kinase inhibitors. The present invention is also directed to certain novel compounds and/or novel solid forms of certain compounds.
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