Substituted pyrrolopyridines and pyrazolopyridines as kinase modulators

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United States of America Patent

PATENT NO 8158647
APP PUB NO 20090005356A1
SERIAL NO

12129546

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Abstract

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Provided herein are substituted pyrrolopyridine heterocycles and substituted pyrazolopyridine heterocycles, pharmaceutical compositions comprising said heterocycles and methods of using said heterocycles in the treatment of disease. The heterocycles disclosed herein function as kinase modulators and have utility in the treatment of diseases such as cancer, allergy, asthma, inflammation, obstructive airway disease, autoimmune diseases, metabolic disease, infection, CNS disease, brain tumor, obesity, asthma, hematological disorder, degenerative neural disease, cardiovascular disease, or disease associated with angiogenesis, neovascularization, or vasculogenesis.

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Patent Owner(s)

Patent OwnerAddress
SGX PHARMACEUTICALS INC10505 ROSELLE STREET SAN DIEGO CA 92121

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Blaney, Jeffrey M San Diego, US 5 315
Gosberg, Andreas San Diego, US 13 1230
Gradl, Stefan N San Diego, US 7 641
Hirst, Gavin San Diego, US 23 549
Hopkins, Stephanie A San Diego, US 5 260
Sprengeler, Paul A San Diego, US 32 725
Steensma, Ruo W San Diego, US 15 1249
Uy, Johnny San Diego, US 29 507

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