Sulfamic acid ester compounds useful in the inhibition of steroid sulphatase activity and aromatase activity
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United States of America Patent
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Apr 3, 2012
Grant Date -
Sep 13, 2007
app pub date -
Nov 22, 2006
filing date -
May 24, 2004
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Abstract
The present invention relates to steroid sulphatase and/or aromatase inhibitors of Formula III or Formula IV, wherein A is selected from H, OH, halogen and hydrocarbyl; D, E and F are each independently of each other an optional linker group; P, Q and R are independently of each other a ring system, wherein R4 and R5 are independently selected from H, alkyl, cycloalkyl, alkenyl, acyl and aryl, or combinations thereof, or together represent alkylene, wherein the or each alkyl or cycloalkyl or alkenyl or optionally contain one or more hetero atoms or groups, and which can be used in medicine.
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