Method for screening allergic disease-related molecule and cell lines to be used in the method
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United States of America Patent
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Apr 3, 2012
Grant Date -
Jul 22, 2010
app pub date -
Nov 14, 2007
filing date -
Nov 14, 2006
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Abstract
An allergic disease-related substance is screened from candidate substances based on the reactivity to a plurality of cell lines, which are basophil-like or mast cell-like cell lines derived from the same spleen tissue and have different sensitivities to allergic cytokines. Further, an allergic disease-related substance is screened from candidate substances using at least one basophil-like or mast cell-like cell lines selected from the group consisting of R cell (Deposit No. FERM BP-10918), N 62.5 cell (Deposit No. FERM BP-10919) and RCCM cell (Deposit No. FERM BP-10920).
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