Bifunctional and trifunctional nitrone spin trapping compounds and uses thereof

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United States of America Patent

PATENT NO 8143420
APP PUB NO 20090170134A1
SERIAL NO

12343975

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Abstract

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Methods and compositions for detecting free radicals, the compositions being spin trapping compounds comprising a nitrone having a detecting moiety and optionally having a targeting moiety for targeting the nitrone to an organ, a cell, an organelle or a molecule of interest for directly detecting free radicals, especially free radicals in biological samples.

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Patent Owner(s)

Patent OwnerAddress
MEDICAL COLLEGE OF WISCONSIN INC8701 WATERTOWN PLANK ROAD MILWAUKEE WI 53226

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hardy, Micael Joel La Seyne sur mer, FR 5 14
Hogg, Neil New Berlin, US 5 36
Kalyanaraman, Balaraman Wauwatosa, US 23 50
Lopez, Marcos Wauwatosa, US 10 46
Ouari, Olivier Seynod, FR 12 9
Tordo, Paul Marsielle, FR 19 97

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