Dalbavancin compositions for treatment of bacterial infections
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United States of America Patent
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Mar 27, 2012
Grant Date -
Dec 3, 2009
app pub date -
Jun 2, 2009
filing date -
Nov 18, 2002
priority date (Note) -
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Abstract
The invention provides methods and compositions for treatment of bacterial infections. The composition may be a combination of factors, which include A0, A1, B1, B2, C0, C1, isoB0, and MAG, in the presence of low level solvent. Methods of the invention include administration of dalbavancin formulations for treatment of a bacterial infection, in particular a Gram-positive bacterial infection of skin and soft tissue. Dosing regimens include multiple dose administration of dalbavancin, which often remains at therapeutic levels in the bloodstream for at least one week, providing prolonged therapeutic action against a bacterial infection. Dosing regimens for renal patients are also included.
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