antagonism and serotonin reuptake inhibition
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United States of America Patent
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Mar 20, 2012
Grant Date -
Sep 4, 2008
app pub date -
Jan 7, 2008
filing date -
Jan 10, 2007
priority date (Note) -
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Abstract
Compounds with a combination of cannabinoid CB1 antagonism and serotonin reuptake inhibition, pharmaceutical compositions containing these compounds, methods for preparing these compounds, methods for preparing novel intermediates useful for their synthesis, and methods for preparing these compositions are disclosed. Uses of such compounds and compositions, particularly their use in administering them to patients to achieve a therapeutic effect in psychosis, anxiety, depression, attention deficits, cognitive disorders, obesity, drug dependence, Parkinson's disease, Alzheimer's disease, pain disorders, neuropathic pain disorders and sexual disorders are disclosed.
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