Systemic purine administration: modulating axonal outgrowth of central nervous system neurons
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United States of America Patent
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Mar 13, 2012
Grant Date -
Sep 3, 2009
app pub date -
Feb 26, 2009
filing date -
Feb 29, 2008
priority date (Note) -
Expired
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Abstract
Methods for modulating the axonal outgrowth of central nervous system neurons are provided by means of internalized purine administration such as by intravenous, intraarterial, subcutaneous, intramuscular, intraperitoneal, and intrapleural administration. The methods are noted for stimulating the axonal outgrowth of central nervous system neurons following an injury (e.g., stroke, traumatic brain injury, cerebral aneurism, spinal cord injury and the like).
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