Inhibition of macrophage-stimulating protein receptor (RON) and methods of treatment thereof
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United States of America Patent
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Mar 13, 2012
Grant Date -
Jun 9, 2011
app pub date -
Dec 14, 2010
filing date -
Nov 21, 2007
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Expired
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Abstract
The invention provides antibodies or fragments thereof, including human antibodies, specific for Macrophage-Stimulating Protein Receptor (MSP-R or RON), which inhibit RON activation. Also provided are methods to inhibit RON, particularly the use of RON antibodies to treat diseases such as cancer.
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