Compounds as PDE IV and TNF inhibitors
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United States of America Patent
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Mar 6, 2012
Grant Date -
Sep 23, 2010
app pub date -
Jan 26, 2010
filing date -
Jul 28, 1993
priority date (Note) -
Expired
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Abstract
This invention is directed to a [di(ether or thioether)heteroaryl or fluoro substituted aryl] compound or an N-oxide thereof or a pharmaceutically acceptable salt thereof, which is useful for inhibiting the production or physiological effects of TNF in the treatment of a patient suffering from a disease state associated with a physiologically detrimental excess of tumor necrosis factor (TNF).
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