Indole derivatives as histamine 3 receptor inhibitors for the treatment of cognitive and sleep disorders, obesity and other CNS disorders

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United States of America Patent

PATENT NO 8129424
APP PUB NO 20110059966A1
SERIAL NO

12943659

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Abstract

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This invention relates to compounds having pharmacological activity, to compositions containing these compounds, and to a method of treatment employing the compounds and compositions. More particularly, this invention concerns certain indole derivatives and their salts and solvates. These compounds have H3 histamine receptor antagonist activity. This invention also relates to pharmaceutical compositions containing these compounds and to a method of treating disorders in which histamine H3 receptor blockade is beneficial.

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Patent Owner(s)

Patent OwnerAddress
ATHERSYS INCCLEVELAND OH

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bennani, Youssef L Boston, US 59 392
Campbell, Michael G Thunder Bay, CA 15 181
Dastrup, David Orem, US 12 30
Huck, Emilie Porter Sudbury, US 7 3

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