Inhibitors of protein phosphatase 1, GADD34 and protein phosphatase 1/GADD34 complex, preparation and uses thereof

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United States of America Patent

PATENT NO 8129340
APP PUB NO 20100016235A1
SERIAL NO

12438833

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Abstract

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The present invention relates to the use of a protein phosphatase inhibitor selected from an inhibitor of the catalytic subunit of the protein phosphatase 1 (PP1), an inhibitor of GADD34 and an inhibitor of the PP1/GADD34 complex to prepare a pharmaceutical composition to prevent or treat a cancer in a mammal, wherein the pharmaceutical composition is intended for administration in combination with a product used in a treatment of a cancer.

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Patent Owner(s)

Patent OwnerAddress
INSTITUT GUSTAVE ROUSSY94805 VILLEJUIF CÉDEX
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)75654 PARIS CÉDEX 13

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kroemer, Guido Antony, FR 36 155
Zitvogel, Laurence Antony, FR 34 232

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