Double-stranded nucleic acid molecule cancer cell proliferation inhibitor and pharmaceutical agent suitable for prevention or treatment of uterine cancer, breast cancer, and bladder cancer

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United States of America Patent

PATENT NO 8124754
APP PUB NO 20100173405A1
SERIAL NO

12642979

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Abstract

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A double-stranded nucleic acid molecule for suppressing the expression of at least one of COX7RP and Efp genes which includes (a) a sense strand which includes a nucleotide sequence corresponding to a target sequence indicated by any one of SEQ ID Nos.: 1 to 38 and (b) an antisense strand which includes a nucleotide sequence complementary to that of the sense strand specified in (a); a cancer cell proliferation inhibitor with the double-stranded nucleic acid molecule and against at least one of uterine, breast and bladder cancer cells; and a pharmaceutical agent with the cancer cell proliferation inhibitor and against at least one of uterine, breast and bladder cancers.

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Patent Owner(s)

Patent OwnerAddress
SAITAMA MEDICAL UNIVERSITY38 MOROHONGO MOROYAMA-MACHI IRUMA-GUN SAITAMA 350-0495
RNAI CO LTDCOSMOS HONGO BLDG 10F 4-1-4 HONGO BUNKYO-KU TOKYO 113-0033

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ikeda, Kazuhiro Saitama, JP 65 219
Inoue, Satoshi Saitama, JP 511 10547

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