Crystalline form of the compound A-348441
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United States of America Patent
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Feb 28, 2012
Grant Date -
Jul 9, 2009
app pub date -
Jul 12, 2006
filing date -
Jul 12, 2005
priority date (Note) -
Expired
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Abstract
There is provided a hemihydrate of (3β,5β,7α,12α)-7,12-dihydroxy-3-{2-[{4-[17β-hydroxy-3-oxo-17α-prop-1-ynylestra-4,9-dien-11β-yl]phenyl}(methyl)amino]ethoxy}cholan-24-oic acid in a crystalline form which is characterised by an X-ray diffraction pattern having major peaks at 2θ=6.58±0.2, 8.54+0.2, 12.28±0.2, and 19.68±0.2. This crystalline material is useful in the treatment of conditions associated with an excess of hepatic glucocorticoid response.
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