Nanoparticulate and controlled release compositions comprising cefditoren
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United States of America Patent
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Feb 21, 2012
Grant Date -
Nov 13, 2008
app pub date -
Feb 5, 2007
filing date -
Nov 2, 1998
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Abstract
The present invention provides a composition comprising a cefditoren, or a salt, derivative, prodrug, or other form thereof, for example, cefditoren pivoxil, useful in the treatment and prevention of infections and related conditions. The invention provides a composition which comprises nanoparticulate particles comprising the cefditoren, or a salt, derivative, prodrug, or other form thereof and at least one surface stabilizer. The nanoparticulate particles have an effective average particle size of less than about 2000 nm. The invention provides also a composition that delivers a cefditoren, or a salt, derivative, prodrug, or other form thereof, or nanoparticles comprising the same, in a pulsatile or continuous manner.
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