Compositions and methods for enhanced gastrointestinal stability of oligopeptides and polypeptides
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United States of America Patent
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Feb 21, 2012
Grant Date -
Dec 18, 2008
app pub date -
Oct 11, 2006
filing date -
Oct 11, 2005
priority date (Note) -
Expired
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Abstract
Methods and compositions are provided for stabilizing polypeptides for oral administration, particularly where enteric delivery is desirable. By administering the polypeptides with a bile sequestering agent, the stability of the polypeptide can be increased. Pharmaceutical formulations for this purpose are provided.
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