Non-integrative and non-replicative lentivirus, preparation and uses thereof
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United States of America Patent
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Feb 21, 2012
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Apr 17, 2008
app pub date -
Jun 24, 2005
filing date -
Jun 25, 2004
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Abstract
The invention concerns a non-integrative and non-replicative recombinant lentivirus as well as its uses, in particular for preparing a composition for transferring genes in vitro, ex vivo or in vivo. The invention is useful for transferring genes in any mammal organism, for example in liver, muscle, pancreas or central nervous system (including the ocular sphere) tissues or cells, and in particular for treating disorders or pathologies such as, for example, central nervous system, including the ocular sphere, disorders.
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