Immunotoxin derived from a recombinant human autoantibody and method of using thereof
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United States of America Patent
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Feb 14, 2012
Grant Date -
Jan 19, 2006
app pub date -
Sep 28, 2004
filing date -
Oct 1, 2003
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Abstract
The invention is directed to an immunotoxin directed at fetal AchR, wherein the immunotoxin may comprises a human Fab fragment based on a human autoantibody or human combinatorial CDNA library and may be a pseudomonas exotoxin A-based single chain Fv IT (35-scFV-ETA). The invention is further directed to method of treating a patient with soft tissue tumor comprising the step of exposing the patient to the immunotoxin of the invention.
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