Pyrazole compounds that modulate the activity of CDK, GSK and aurora kinases
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United States of America Patent
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Feb 7, 2012
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Jun 5, 2008
app pub date -
Dec 30, 2005
filing date -
Dec 30, 2004
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Abstract
The invention provides a compound of the formula (I): or a salt, solvate, tautomer or N-oxide thereof, wherein M is selected from a group D1 and a group D2: and R′, E, A and X are as defined in the claims. Also provided are pharmaceutical compositions containing the compounds, processes for making the compounds and the use of the compounds in the prophylaxis or treatment of a disease state mediated by a CDK kinase, GSK-3 kinase or Aurora kinase.
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