Non-proteolysable oligopeptides that inhibit glycoprotein GP41 of the aids virus
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United States of America Patent
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Feb 7, 2012
Grant Date -
Aug 5, 2010
app pub date -
Dec 29, 2006
filing date -
Dec 30, 2005
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Abstract
The invention relates to non-proteolysable oligopeptides that inhibit glycoprotein 41 of the AIDS virus. More specifically, the invention relates to the identification of oligopeptides, particularly hexapeptides, (D), (L) or mixed, preferably D-hexapeptides, which inhibit the binding of a retrovirus to a target cell, thereby providing novel therapies against infection from the human immunodeficiency virus (HIV). The invention also relates to the use of said D-hexapeptides in the form of single components or complex mixtures as prophylactic or therapeutic agents for retroviral infections, especially human immunodeficiency virus type 1 (HIV-1).
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