N-terminal modified interferon-alpha

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United States of America Patent

PATENT NO 8106160
APP PUB NO 20090269306A1
SERIAL NO

12243227

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Abstract

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A method of reducing formation of non-natural disulfide bonds in a mature IFN-α by adding one or more amino acid residues to its N-terminus cystein. Also disclosed herein is the IFN-α thus modified.

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Patent Owner(s)

Patent OwnerAddress
PHARMAESSENTIA CORPTAIPEI 115

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hsu, Ming-Pin Taipei, TW 2 0
Shen, Tsai-Kuei Sanchong, TW 2 0
Teng, Ching-Leou San Diego, US 8 261
Wu, Bryan T H Taipei, TW 4 3

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