Aβ binding molecules
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United States of America Patent
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Jan 31, 2012
Grant Date -
Dec 3, 2009
app pub date -
Jul 17, 2009
filing date -
Feb 10, 2003
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Abstract
The present invention encompasses isolated antibodies, or fragments thereof, that are humanized variants of murine antibody 266 which employ complementarily determining regions derived from murine antibody 266. The variant antibodies are useful for treatment or prevention of conditions and diseases associated with Aβ, including Alzheimer's disease. Down's syndrome, cerebral amyloid angiopathy, mild cognitive impairment, and the like.
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