Method of storing thermoresponsive polymer in state of aqueous solution
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United States of America Patent
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Jan 31, 2012
Grant Date -
Sep 29, 2011
app pub date -
May 31, 2011
filing date -
Jun 29, 2007
priority date (Note) -
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Abstract
It is intended to provide an aqueous solution of a thermoresponsive polymer, which shows an upper critical solution temperature (UCST) and is capable of maintaining a dissolved state, even if it is stored for a long period of time at a temperature at which a ligand such as an antibody or an antigen is not inactivated. A UCST lowering agent is incorporated in a predetermined amount in an aqueous solution of a thermoresponsive polymer which shows a UCST in a state of containing water, thereby lowering the UCST of the aqueous solution to less than the storage temperature, and the resulting aqueous solution is stored.
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