Polymorphic form of lercanidipine hydrochloride and process for the preparation thereof
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United States of America Patent
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Jan 17, 2012
Grant Date -
Sep 3, 2009
app pub date -
Sep 18, 2006
filing date -
Sep 16, 2005
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Abstract
Processes for the purification of lercanidipine hydrochloride are provided which uses a binary system of an alcohol-containing solvent such as methanol and an aliphatic ester-containing solvent such as isopropyl acetate. Processes for the preparation of substantially amorphous lercanidipine hydrochloride are also provided. Also provided is lercanidipine hydrochloride substantially in polymorph form V.
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