Nitrogenated trans-stilbene analogs, method for the obtention and medical applications thereof

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United States of America Patent

PATENT NO 8097656
APP PUB NO 20110060038A1
SERIAL NO

12861581

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Abstract

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This invention is related to new nitrogenated trans-stilbene compounds, more specifically, imine, pyrrole and indole derivatives, with procedures for the preparation and use thereof as pharmaceutical compositions for the treatment and/or chemoprevention of those mammalian diseases such as cancer, fibrosclerosis and acute/chronic inflammation, graft-versus-host reaction, ischemic-reperfusion tissue injury in stroke and heart attack, neurodegeneration, and during organ transplantation, whose pathogenic and pathophysiological mechanisms depend on or are significantly contributed by undesirable oxidative stress, angiogenic and proliferative responses.

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Patent Owner(s)

Patent OwnerAddress
DOMINION PHARMAKINE S LEDIFICIO 801A 1A PLANTA PARQUE TECNOLOGICO DE BIZKAIA DERIO (BIZKAIA) E-48160

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Amato, Silvia Vivanco Leioa, ES 3 3
Arevalo, Eneko Aldaba Leioa, ES 3 3
Arteche, Miren Lorea Mendoza Derio, ES 2 2
Cossio, Fernando Pedro Leioa, ES 3 3
Escobal, Natalia Gallot Derio, ES 2 1
Olascoaga, Aizpea Zubia Leioa, ES 2 1
Pogonza, Clarisa Salado Derio, ES 2 1
Salazar, Yosu Ion Vara Leioa, ES 3 3
Vanaclocha, Fernando Vidal Derio, ES 3 3

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