Fused thiazole derivatives as kinase inhibitors

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United States of America Patent

PATENT NO 8093238
APP PUB NO 20100069361A1
SERIAL NO

12445056

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Abstract

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A series of 5,5-dimethyl-5,6-dihydro-1,3-benzothiazol-7(4H)-one and 7,7-dimethyl-5,6,7,8-tetrahydro-4H-[1,3]thiazolo[5,4-c]azepin-4-one derivatives, and analogues thereof, which are substituted in the 2-position by an optionally substituted benzofused morpholin-4-yl moiety, being selective inhibitors of PI3 kinase enzymes, are accordingly of benefit in medicine, for example in the treatment of inflammatory, autoimmune, cardiovascular, neurodegenerative, metabolic, oncological, nociceptive or ophthalmic conditions. Formula (I).

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Patent Owner(s)

Patent OwnerAddress
UCB PHARMA S A1070 BRUSSELS

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Buckley, George Martin Slough, GB 9 238
Morgan, Trevor Slough, GB 9 39
Sabin, Verity Margaret Slough, GB 14 254

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