Alkynyl pyrrolo[2,3-d]pyrimidines and related analogs as HSP90-inhibitors
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United States of America Patent
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Jan 10, 2012
Grant Date -
Dec 24, 2009
app pub date -
May 22, 2009
filing date -
Mar 30, 2005
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Abstract
Alkynyl pyrrolo [2,3-d] pyrimidines of Formula I are described and demonstrated to have utility as Heat Shock Protein 90 (HSP90) inhibiting agents used in the treatment and prevention of various HSP90 mediated disorders. Methods of synthesis and use of such compounds are also described and claimed.
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