Preparation and use of a reactive solid support surface
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United States of America Patent
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Jan 10, 2012
Grant Date -
Feb 18, 2010
app pub date -
Oct 19, 2009
filing date -
Oct 13, 2004
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Abstract
A method of preparing a protein-resistant reactive solid support surface is disclosed. The method comprises the steps of providing a solid support having a hydrogel coating with a plurality of binding elements, coupling a protein resistant compound to the hydrogel via a first fraction of the binding elements, and coupling at least one binding agent to the hydrogel via a second fraction of the binding elements, whereby the protein resistant compound and the at least one binding agent are co-immobilized to the hydrogel. Also the use of the reactive surface in analysis, such as immunogenicity assays, is disclosed.
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