ENT-kaurene diterpene compound and its derivatives, their preparation and their use

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United States of America Patent

PATENT NO 8084430
APP PUB NO 20100228014A1
SERIAL NO

12160359

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Abstract

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Novel ent-kaurene diterpene compound and its derivatives, their preparation methods and their use. ent-Kaurene diterpene in the present invention could be used as desired intermediates for preparing asymmetric organic compounds and medicaments, and could be used as antitumor agent, anti-inflammatory agent and immune agent etc. The said ent-kaurene diterpene compound could be condensed with hydroxyl compounds to obtain various acetal derivatives, could be reacted with amine compounds to obtain various amino derivatives, and could be reacted with acyl halide or acid anhydride to obtain various acyl derivatives.

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Patent Owner(s)

Patent OwnerAddress
ZHENGZHOU UNIVERSITYNO 100 SCIENCE AVENUE GAOXIN DISTRICT ZHENGZHOU HENAN 450000 450000
FUREN PHARMACEUTICALSUOKE BUILDING 9F DONGMING ROAD #218 ZHENGZHOU HENAN 450008

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Jianye, Zhang Zhengzhou, CN 1 2
Ke, Yu Zhengzhou, CN 2 6
Liu, Hongmin Zhengzhou, CN 10 8
Liu, Zhengzhou Zhengzhou, CN 1 0
Qu, Hongli Zhengzhou, CN 1 2
Wang, Qingduan Zhengzhou, CN 1 2
Yan, Xuebin Zhengzhou, CN 4 18
Zhu, Chenggong Zhengzhou, CN 2 2
Zhu, Wenchen Zhengzhou, CN 2 2

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