Method for analysing polynucleotide targets using tethered oligonucleotide probes
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United States of America Patent
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Dec 27, 2011
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May 17, 2007
app pub date -
Sep 7, 2006
filing date -
Apr 7, 1995
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Abstract
A method of analysing a polynucleotide target involves incubating the target with an oligonucleotide probe, generally an array of immobilised oligonucleotide probes, to form a duplex, and using ligase or polymerase to extend one chain of the duplex. A point mutation or variable number tandem repeat section may be analysed. Arrays of immobilised oligonucleotides are provided for use in the method.
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