Process for recycling solid supports for cultivation of anchorage-dependent cells
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United States of America Patent
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Dec 20, 2011
Grant Date -
Aug 30, 2007
app pub date -
Nov 26, 2004
filing date -
Nov 28, 2003
priority date (Note) -
Expired
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Abstract
This invention relates to methods for use in industrial production of proteins. Specifically, the present invention provides a method of recycling solid supports for cultivation of anchorage-dependent cells such as, e.g., microcarriers and Fibra-Cel® disks. Solid supports recycled by a method of the present invention allow obtaining a protein productivity level comparable to the productivity level obtained with non-recycled solid support. The method comprises the steps of rinsing with water, rinsing with a sodium hydroxide solution and second rinsing step with water.
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