Methods for production of oligonucleotides

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United States of America Patent

PATENT NO 8080393
APP PUB NO 20100028953A1
SERIAL NO

11911521

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention relates to production of oligonucleotides using rolling circle replication, wherein synthesised multimeric oligonucleotides are reduced to mononucleotides using a nicking cassette. Thus, the invention provides a method for the production of oligonucleotides, enabling efficient amplification of oligonucleotides at lengths up to at least 1000 nucleotides and in high amounts contained within a nicking cassette.

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Patent Owner(s)

Patent OwnerAddress
ZIMMER GMBHSULZER-ALLEE 8 WINTERTHUR CH-8404

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Koch, Jorn Erland Ry, DK 2 57
Lohmann, Jakob Schwalbe Ry, DK 4 108
Stougaard, Magnus Aarhus C, DK 10 109

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