Stable recombinant adenosine deaminase
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United States of America Patent
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Dec 6, 2011
Grant Date -
Feb 19, 2009
app pub date -
Apr 18, 2008
filing date -
Apr 20, 2007
priority date (Note) -
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Abstract
A mutein recombinant adenosine deaminase having any oxidizable cysteine residue replaced by a non-oxidizable amino acid residue is disclosed. Stabilized recombinant adenosine deaminase, polymer conjugates and methods of treatment using the same are also disclosed.
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