Model animal causing the white hair development and methods relating thereto
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United States of America Patent
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Nov 29, 2011
Grant Date -
Mar 26, 2009
app pub date -
Feb 10, 2006
filing date -
Jul 1, 2005
priority date (Note) -
Expired
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Abstract
A model rodent animal with a phenotype in which hair growing after birth is black, with the animal spontaneously developing white hair after aging. By way of example, the model rodent animal may have a genotype in which an activated RET gene is genetically inserted in a heterozygous form and the endothelin receptor B gene is deficient in a heterozygous form.
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