Antibodies against T cell immunoglobulin domain and mucin domain 1 (TIM-1) antigen and uses thereof
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United States of America Patent
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Nov 29, 2011
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app pub date -
Mar 19, 2004
filing date -
Mar 19, 2003
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Abstract
The invention described herein is related to antibodies directed to the antigen TIM-1 and uses of such antibodies. In particular, there are provided fully human monoclonal antibodies directed to the antigen TIM-1. Isolated polynucleotide sequences encoding, and amino acid sequences comprising, heavy and light chain immunoglobulin molecules, particularly sequences corresponding to contiguous heavy and light chain sequences spanning the framework regions (FR's) and/or complementarity determining regions (CDR's), specifically from FR1 through FR4 or CDR1 through CDR3, are provided. Hybridomas or other cell lines expressing such immunoglobulin molecules and monoclonal antibodies are also provided.
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