Immunogenic T-helper epitopes from human tumour antigens and immunotherapeutic methods using said epitopes

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United States of America Patent

PATENT NO 8067529
APP PUB NO 20090317428A1
SERIAL NO

11664627

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Abstract

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The present invention relates to immunotherapeutic methods, and molecules and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer, in particular renal cancer. The present invention furthermore relates to tumour-associated T-helper cell peptide epitopes, alone or in combination with other tumour-associated peptides, that serve as active pharmaceutical ingredients of vaccine compositions which stimulate anti-tumour immune responses. In particular, the present invention relates to 338 novel peptide sequences derived from HLA class II molecules of human tumour cell lines which can be used in vaccine compositions for eliciting anti-tumour immune responses.

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Patent Owner(s)

Patent OwnerAddress
IMMATICS BIOTECHNOLOGIES GMBHPAUL-EHRLICH-STR 15 TÜBINGEN 72076

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Dengjel, Jörn Tübingen, DE 8 367
Rammensee, Hans-Georg Tübingen-Unterjesingen, DE 98 728
Weinschenk, Toni Esslingen, DE 760 8126

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