Decoy-containing pharmaceutical compositions and method of using the same
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United States of America Patent
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Nov 29, 2011
Grant Date -
Dec 30, 2010
app pub date -
Jan 7, 2009
filing date -
Feb 1, 2002
priority date (Note) -
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Abstract
A pharmaceutical composition is provided for treatment and prevention of a disease caused by expression of a gene controlled by NF-κB or ets. The composition comprises at least one decoy and a pharmaceutically acceptable carrier. The decoy is an NF-κB decoy, an ets decoy, or a chimera decoy of NF-κB and ets. The disease is cerebral aneurysm, cancer, Marfan's syndrome, aortic detachment, post-angioplasty restenosis, chronic articular rheumatism, asthma, atopic dermatitis, nephritis, renal failure, or plaque rupture. The pharmaceutically acceptable carrier may be a hydrophilic polymer.
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