Optimized human T1R3 nucleic acid molecule
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United States of America Patent
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Nov 29, 2011
Grant Date -
May 13, 2010
app pub date -
Nov 11, 2009
filing date -
Jun 7, 2006
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Abstract
The present invention relates to a screening system for modulators of GPCRs. Further it relates to recombinant vector systems for the heterologous expression of heterodimeric g-protein coupled receptors (GPCRs) in eukaryotic host cells. Preferably the functional expression of engineered GPCRs for the perception of sweet and L-amino acid taste or more preferably the use of these receptors for the identification of functional ligands is also encompassed.
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