Salts and polymorphs of desazadesferrithiocin polyether analogues as metal chelation agents
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United States of America Patent
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Nov 22, 2011
Grant Date -
Jun 3, 2010
app pub date -
Jul 14, 2009
filing date -
Jul 14, 2008
priority date (Note) -
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Abstract
Disclosed herein are new salts and polymorphs of desazadesferrithiocin polyether (DADFT-PE) analogues, as well as pharmaceutical compositions comprising them and their application as metal chelation agents for the treatment of disease. Methods of chelation of iron and other metals in a human or animal subject are also provided for the treatment of metal overload and toxicity.
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