Method for treating a brain cancer with ifenprodil
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United States of America Patent
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Nov 15, 2011
Grant Date -
Mar 19, 2009
app pub date -
Oct 12, 2007
filing date -
Oct 13, 2006
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Abstract
A clonogenic neurosphere assay is described that carries out high throughput screens (HTS) to identify potent and/or selective modulators of proliferation, differentiation and/or renewal of neural precursor cells, neural progenitor cells and/or self-renewing and multipotent neural stem cells (NSCs). Compositions comprising the identified modulators and methods of using the modulators and compositions, in particular to treat neurological disorders (e.g. brain or CNS cancer) or damage are also disclosed.
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