Method and system for suppressing bindings on magnetic particles
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United States of America Patent
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Nov 8, 2011
Grant Date -
Dec 31, 2009
app pub date -
Jun 27, 2008
filing date -
Jun 27, 2008
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Abstract
A method for suppressing non-specific bindings between molecules includes providing magnetic particles dispersed in a liquid, wherein each of the magnetic particles has a magnetization. The magnetic particles are coated with coating molecules. Binding molecules mixed of first-type binding molecules and second-type binding molecules are applied to the liquid, wherein the coating molecules are specifically binding with the first-type binding molecules and non-specifically binding with the second-type binding molecules. An alternating current (ac) magnetic field is applied at an axis with a frequency level, wherein the frequency level causes suppression of the second-type binding molecules in binding with the coating molecules.
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