Host cells expressing IL-18 receptors
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United States of America Patent
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Nov 8, 2011
Grant Date -
Jul 29, 2010
app pub date -
Mar 3, 2010
filing date -
Jan 23, 1998
priority date (Note) -
Expired
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Abstract
A novel polypeptide that functions as an IL-18 receptor is disclosed. The receptor is multimeric and includes at least one AcPL polypeptide, or fragment thereof, and at least one IL-1Rrp1 polypeptide, or fraction thereof. The receptor binds IL-18 and finds use in inhibiting biological activities mediated by IL-18.
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