Treatment of hyperproliferative diseases
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United States of America Patent
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Nov 1, 2011
Grant Date -
Jun 26, 2003
app pub date -
Feb 27, 2002
filing date -
Aug 17, 2000
priority date (Note) -
Expired
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Abstract
We describe methods and compositions for treating a patient suffering from a hyperproliferative disorder or photoageing. Our methods involve blocking the activity of a retinol binding protein receptor (RBPr) in cells of the patient, and/or administering to the patient an antagonist of a retinol binding protein receptor (RBPr) and/or lowering the endogenous level of retinoic acid (RA) in cells of said patient.
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