Osteogenic composite matrix, method for the production thereof and implant and scaffold for tissue engineering provided with a coating formed by said osteogenic composite matrix

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United States of America Patent

PATENT NO 8043627
APP PUB NO 20100119575A1
SERIAL NO

12572884

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Abstract

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The invention relates to an osteogenic composite matrix consisting of collagen and non-collagen components of an extracellular matrix (ECM-components), to a method for producing said matrix, to a method for producing an implant or a scaffold for tissue engineering which is provided with a coating formed by said osteogenic composite matrix and is used for stimulating and accelerating a hard tissue formation such as, for example. The implant osseointegration in bones. The inventive osteogenic composite matrix comprises a collagen and at least one non-collagen ECM component or the derivatives thereof, wherein the collagen component consists of non-crosslinked collagen fibers produced by fibrillogenesis and the non-collagen ECM component or the derivatives thereof are integrated into said collagen fibers.

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Patent Owner(s)

Patent OwnerAddress
NEXILIS AG4410 LIESTAL

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bierbaum, Susanne Dresden, DE 2 5
Scharnweber, Dieter Dresden, DE 8 105
Worch, Hartmut Dresden, DE 13 140

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