Met fab and SCFV fragments
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United States of America Patent
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Oct 18, 2011
Grant Date -
Dec 31, 2009
app pub date -
Jan 21, 2008
filing date -
Jan 19, 2007
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Abstract
Antibody fragments (Fabs and scFvs) specific to the Met receptor are disclosed. Compositions and kits including these Fabs and scFvs, and drug and imaging conjugates of these Fabs and scFvs also are disclosed. The novel Fabs and scFvs can be internalized into the interior of a cell. Methods include using the novel Met Fabs and scFvs for diagnosing, prognosing, and treating cancer, and for evaluating chemotherapeutic response.
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